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All I need to know about DanioScope

DanioScope has been used for many different applications. On this page you can find some of the blogs we have written for you to enlighten you on the applications of DanioScope. We have also compiled a list of recently published papers by application.

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The ins and outs of zebrafish research

Basic behavioral neuroscience in zebrafish

Learn all about the why, when and how regarding zebrafish development and behavior

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Featured blog posts

A zebrafish model for ALS-related gene mutations

How zebrafish are helping us to discover the mechanisms behind this neurodegenerative disease.

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Using zebrafish as an early warning system of neurotoxic substances

How can we use a zebrafish (Danio rerio) embryo model to detect possible neurotoxic chemical mixtures that are difficult to detect with normal chemical analyses?

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Breathe easy, a novel appraoch to monitoring respiratory activity in zebrafish

Researchers from the University of Heidelberg used DanioScope in a novel way to objectively measure breathing in zebrafish embryos and larvae.

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Relevant publications

Here is an overview of some recent publications with DanioScope. If you feel like your publication should be on this list, send us an e-mail at: [email protected].
Bertoni, Í.; Sales, B.C.P.; Viriato, C.; Peixoto, P.V.L.; Pereira, L.C. Embryotoxicity Induced by Triclopyr in Zebrafish (Danio Rerio) Early Life Stage. Toxics 2024, 12, 255.

Derkaczew, M.; Kędziora, B.; Potoczna, M.; Podlasz, P.; Wąsowicz, K.; Jóźwik, M.; Wojtkiewicz, J. The Study of Myo-Inositol’s Anxiolytic Activity on Zebrafish (Danio Rerio). Nutrients 2024, 16, 1997.

Du, Y.; Li, Q.; Zhou, G.; Cai, Z.; Man, Q.; Wang, W.C. Early-Life Perfluorooctanoic Acid Exposure Disrupts the Function of Dopamine Transporter Protein with Glycosylation Changes Implicating the Links between Decreased Dopamine Levels and Disruptive Behaviors in Larval Zebrafish. Sci. Total Environ. 2024, 917, 170408.

Miles, K.D.; Barker, C.M.; Russell, K.P.; Appel, B.H.; Doll, C.A. Electrical Synapses Mediate Embryonic Hyperactivity in a Zebrafish Model of Fragile X Syndrome. J. Neurosci. 2024, 44.
Correia, D.; Bellot, M.; Goyenechea, J.; Prats, E.; Moro, H.; Gómez-Canela, C.; Bedrossiantz, J.; Tagkalidou, N.; Ferreira, C.S.; Raldúa, D. Parental Exposure to Antidepressants Has Lasting Effects on Offspring? A Case Study with Zebrafish. Chemosphere 2024, 355, 141851.

Mu, X.; Liu, Z.; Zhao, X.; Yuan, L.; Li, Y.; Wang, C.; Xiao, G.; Mu, J.; Qiu, J.; Qian, Y. Bisphenol A Analogues Induce Neuroendocrine Disruption via Gut–Brain Regulation in Zebrafish. Environ. Sci. Technol. 2024, 58, 1022–1035, doi:10.1021/acs.est.3c05282.
Schimith, L.E.; Machado Da Silva, V.; Costa-Silva, D.G.D.; Seregni Monteiro, L.K.; Muccillo-Baisch, A.L.; André-Miral, C.; Hort, M.A. Preclinical Toxicological Assessment of Polydatin in Zebrafish Model. Drug Chem. Toxicol. 2024, 1–10, doi:10.1080/01480545.2024.2311287.

Da’as, S.I.; Thanassoulas, A.; Calver, B.L.; Saleh, A.; Abdelrahman, D.; Hasan, W.; Safieh‐Garabedian, B.; Kontogianni, I.; Nasrallah, G.K.; Nounesis, G.; et al. Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function. J. Cell. Biochem. 2024, 125, e30619, doi:10.1002/jcb.30619.

Liu, Y.; Jin, X.; Ye, Y.; Xu, Z.; Du, Z.; Hong, H.; Yu, H.; Lin, H.; Huang, X.; Sun, H. Emerging Disinfection Byproducts 3-Bromine Carbazole Induces Cardiac Developmental Toxicity via Aryl Hydrocarbon Receptor Activation in Zebrafish Larvae. Environ. Pollut. 2024, 346, 123609.
Marchese, M.; Bernardi, S.; Ogi, A.; Licitra, R.; Silvi, G.; Mero, S.; Galatolo, D.; Gammaldi, N.; Doccini, S.; Ratto, G.M. Targeting Autophagy Impairment Improves the Phenotype of a Novel CLN8 Zebrafish Model. Neurobiol. Dis. 2024, 197, 106536.

Missawi, O.; Wouters, C.; Lambert, J.; Garigliany, M.-M.; Kestemont, P.; Cornet, V. Realistic Microplastics Harness Bacterial Presence and Promote Impairments in Early Zebrafish Embryos: Behavioral, Developmental, and Transcriptomic Approaches. Chemosphere 2024, 350, 141107.

Sampaio, C.F.; Gravato, C.; de Oliveira, D.P.; Dorta, D.J. Deleterious Effects of Benzotriazoles on Zebrafish Development and Neurotransmission: 5-Chloro-Benzotriazole versus 1H-Benzotriazole. Sci. Total Environ. 2024, 912, 168741.
Kämmer, N.; Reimann, T.; Ovcharova, V.; Braunbeck, T. A Novel Automated Method for the Simultaneous Detection of Breathing Frequency and Amplitude in Zebrafish (Danio Rerio) Embryos and Larvae. Aquat. Toxicol. 2023, 258, 106493.

Kämmer, N.; Reimann, T.; Braunbeck, T. Neurotoxic Pesticides Change Respiratory Parameters in Early Gill-Breathing, but Not in Skin-Breathing Life-Stages of Zebrafish (Danio Rerio). Aquat. Toxicol. 2024, 267, 106831.