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EthoVision XT

Resources and publications

EthoVision XT is the most widely applied video tracking software that tracks and analyzes the behavior, movement, and activity of any animal.

  • A cost-effective solution for all standard behavioral tests
  • High-throughput and high-content testing
  • Suitable for sophisticated test-protocols

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EthoVision publication power

Training when you need it: Noldus Academy

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Noldus is thrilled to present Noldus Academy, a learning platform aimed at achieving research excellence through expert training and support. Our EthoVision® XT onboarding training is now available in the academy!

Gain exclusive access to Noldus Academy with NoldusCare. Don't have NoldusCare? No worries, the first sample lesson is on us! And if you feel comfortable after this first lesson, feel free to contact us and ask about the pricing options.

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Your essential research toolkit

Free e-book

Want to know more about behavioral neuroscience? Check out our free downloadable e-book where we explain from A to Z why and how we measure certain behavior in rodents, what they translate to and how you can you put EthoVision XT to the most advantage in your research.

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Free buyer's guide

Want to know more about the perfect video tracking setup? Already have the basics down and looking for the best solution for your behavioral research? Our video tracking buyer’s guide lays out the groundwork for you and compares all the options out there on the market.

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Get to know EthoVision XT

EthoVision XT: Product tour

Why EthoVision XT is the market leader

3 tips for better tracking

Learn about EthoVision XT in two minutes

Customer success story

Using EthoVision XT as an education tool

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EthoVision XT in action

Water maze testing and Alzheimer’s

The Morris Water maze test is one of the most used tests for spatial learning and memory in behavioral neuroscience. Read about how EthoVision XT is ideal for this test!

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Epilepsy research in zebrafish

The development of accurate, high-throughput models for epilepsy research is crucial. Read how researchers use EthoVision XT to develop a multi-parametric analysis in zebrafish.

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Fear conditioning

Fear- a highly conserved behavior in rodents. Read about how EthoVision XT automates this test and accurately measures freezing behavior in this Pavlovian learning tasks for rodents.

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Download our case studies

Olfactory HaXha

Verhagen and his colleagues used the olfactory habituation/cross-habituation test as a non-invasive spontaneous behavioral task that has been used to study the ability to smell and the capacity to discriminate between stimuli (odors).

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Effects of early life stress

In order to study whether learning and memory is altered after early stress, Oomen and her colleagues subjected male rats to maternal deprivation and tested their spatial learning ability and emotional memory in adulthood.

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Mice avoidance learning

Maroteaux and his colleagues focussed their research project on the complex behavioral response of avoidance learning in mice, using an unsupervised, automated high throughput system: the PhenoTyper.

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Selected publications

EthoVision XT is the preferred behavioral tool for scientists that publish in high impact journals.
Sulukan, E. et al. (2023). Global warming and glyphosate toxicity (II): Offspring zebrafish modelling with behavioral, morphological and immunohistochemical approaches. Science of The Total Environment, 856 (1). https://doi.org/10.1016/j.scitotenv.2022.158903
Caporale, N. et al (2022). From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures. Science, vol 375 issue 6582. https://doi.org/10.1126/science.abe8244
Rehman, S. et al (2022). Developmental defects and behavioral changes in a diet-induced inflammation model of zebrafish. Frontiers in Immunology, volume 13 - 2022. https://doi.org/10.3389/fimmu.2022.1018768
Johnson, A. et al (2023). Examining behavioural test sensitivity and locomotor proxies of anxiety-like behaviour in zebrafish. Scientific reports, volume 13, Article number: 3768 (2023). https://doi.org/10.1080/00140139.2022.2157493.
Singh, H. et al (2022). Learning Deficits and Attenuated Adaptive Stress Response After Early-Life Seizures in Zebrafish. Frontiers in Neuroscience, Volume 16 - 2022. https://doi.org/10.3389/fnins.2022.869671
Gabellini, C. et al (2022). CRISPR/Cas9-Induced Inactivation of the Autism-Risk Gene setd5 Leads to Social Impairments in Zebrafish. International Journal of Molecular Sciences, 2023, 24(1), 167. https://www.mdpi.com/1422-0067/24/1/167
Zheng, J. et al (2022). Knockout of Katnal2 Leads to Autism-like Behaviors and Developmental Delay in Zebrafish. International Journal of Molecular Sciences, 2022, 23 (15). https://doi.org/10.3389/frcha.2023.1214890
Birnie, M.T. et al (2023). Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice. Nature Communications, 14, Article number: 1088. https://doi.org/10.1038/s41467-023-36780-x
Byun, Y., & Noh, J. (2024). Social play exclusion model in adolescent rats: Monitoring locomoter and emotional behavior associated with social play and examining c-Fos expression in the brain. Physiology & Behavior, 273, Article number: 114379. https://doi.org/10.1016/j.physbeh.2023.114379
Oh, H. et al (2023). Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice. Nature Communications, 14, Article number: 3547. https://doi.org/10.1038/s41467-023-39203-z
Liu, J. et al (2022). GW4064 Alters Gut Microbiota Composition and Counteracts Autism-Associated Behaviors in BTBR T+tf/J Mice. Frontiers in Cellular and Infection Microbiology, Volume 12 - 2022. https://doi.org/10.3389/fcimb.2022.911259
Cassidy, B.R. et al (2023). Progressive cognitive impairment after recovery from neuroinvasive and non-neuroinvasive Listeria monocytogenes infection. Frontiers in Immunology, volume 14 - 2023. https://doi.org/10.3389/fimmu.2023.1146690
Cassidy, B.R. et al (2023). Systemic infection of mice with neuroinvasive Listeria monocytogenes triggers cognitive decline and persistent increases in brain CD8+ T-lymphocyte populations. Journal of Affective Disorders Reports, Volume 12 (100536). https://doi.org/10.1016/j.jadr.2023.100536
Hendrickx, J.O. et al (2022). Age-related cognitive decline in spatial learning and memory of C57BL/6J mice. Behavioral Brain Research, Volume 418. https://doi.org/10.1016/j.bbr.2021.113649
Williams, Z.A.P. et al (2023). Sex-specific effects of voluntary wheel running on behavior and the gut microbiota-immune-brain axis in mice. Brain, Behavior, & Immunity - Health, Volume 30 (100628). https://doi.org/10.1016/j.bbih.2023.100628
Xu, N. et al (2022). Adiponectin Ameliorates GMH-Induced Brain Injury by Regulating Microglia M1/M2 Polarization Via AdipoR1/APPL1/AMPK/PPARγ Signaling Pathway in Neonatal Rats. Frontiers in Immunology, volume 13 - 2022. https://doi.org/10.3389/fimmu.2022.873382
Kafle, B.D., Bernal, J.S. & Fadamiro, H.Y. (2025). Three-dimensional flight analysis shows associative learning enhances foraging behavior of the specialist parasitoid, Microplitis croceipes. Entomologia Experimentalis et Applicata 00, 1–10. https://doi.org/10.1111/eea.13560
Ilie, O. D., Duta, R., Jijie, R., Nita, I. B., Nicoara, M., Faggio, C., Dobrin, R., Mavroudis, I., Ciobica, A., & Doroftei, B. (2022). Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson’s Disease Chronically Exposed to Rotenone. Brain Sciences, 12(7), 898. https://doi.org/10.3390/brainsci12070898
Jijie, R., Solcan, G., Nicoara, M., Micu, D., & Strungaru, S. A. (2020). Antagonistic effects in zebrafish (Danio rerio) behavior and oxidative stress induced by toxic metals and deltamethrin acute exposure. Science of the Total Environment, 698, 134299. https://doi.org/10.1016/j.scitotenv.2019.134299
Hinze, A., Lantz, J., Hill, S. R., & Ignell, R. (2021). Mosquito host seeking in 3D using a versatile climate-controlled wind tunnel system. Frontiers in behavioral neuroscience, 15, 643693. https://doi.org/10.3389/fnbeh.2021.643693

Trusted partners, ethical standards, and expert webinars

Our partners

In this network of partners, we keep on building new opportunities for your research.

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Ethics and animal testing

Animals are sentient beings and deserve our respect. Their invaluable contribution to scientific research requires that we provide them with what they need for a good life, as much as we can.

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Learn from experts

Over the last few years, we have hosted several webinars and technical briefings. To replay for free, simply register for the webinar of your choice!

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